The production of fibroblast growth factor 23 is controlled by TGF-β2
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چکیده
منابع مشابه
Vascular Endothelial Growth Factor Production is Regulated by Gene Polymorphisms
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Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that regulates phosphate homeostasis and when elevated increases cardiovascular disease and stroke risk and mortality. However, most studies of FGF23 have focused on those with chronic kidney disease (CKD). Less data are available from the general population, especially with respect to stroke. We previously reported elevated FGF23 in...
متن کاملHow fibroblast growth factor 23 works.
There is a discontinuum of hereditary and acquired disorders of phosphate homeostasis that are caused by either high or low circulating levels of the novel phosphaturic hormone fibroblastic growth factor 23 (FGF23). Disorders that are caused by high circulating levels of FGF23 are characterized by hypophosphatemia, decreased production of 1,25-dihydroxyvitamin D, and rickets/osteomalacia. On th...
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Fibroblast growth factor (FGF)-2, which stimulates DNA synthesis by type II cells in the lung, has been shown to be regulated by transforming growth factor (TGF)-beta1, an important inflammatory cytokine, in vascular epithelium. The goal of this study was to determine if FGF-2 production by alveolar type II cells is modulated by TGF-beta1 or FGF-1, which also stimulates DNA synthesis by type II...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-05226-y